pozorvlak: (babylon)
pozorvlak ([personal profile] pozorvlak) wrote2007-10-25 10:41 am
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Contraceptive failure

This point came up in a conversation over on [livejournal.com profile] steerpikelet's LJ, and I thought it bore repeating here. Partly because it's important, but mostly because it allows me to talk about one of my favourite bits of maths, namely probability theory.

The failure rates of contraceptives are invariably quoted per year, rather than per use. So when people say that condoms have a breakage rate of 3%, this does not mean that for every 100 condoms you use, you can expect 3 to split: it means that for every 100 couples who have been using condoms for a year, 3 couples will have had at least one condom split on them. The difference is dramatic; let's see what would have happened if 3% of condoms split. In that case, every time you use a condom, it has a 97% chance of not splitting. So if you use, say, 100 condoms, the chance you won't experience any breaks at all is the product of the probabilities of each condom not breaking, i.e. 0.97 x 0.97 x ... x 0.97 = 0.97^100 = 0.047... . Which is to say that if 3% of condoms split, and you had sex 100 times in a year, you'd have only a 5% chance of not experiencing at least one broken "condom". And you'd have more than an 80% chance of experiencing two or more condom breakages in that year: the probability of exactly one condom breaking is 0.03 (for the broken condom) x 0.97^99 (for the 99 unbroken ones) x 100 (choices for which condom is the broken one) = 0.147, so the probability of two or more breaking is 1 - P(none break) - P(exactly one breaks) = 1 - 0.047 - 0.147 =~ 0.806. Such a "contraceptive" would be effectively useless.

"Blimey, guv'nor," I hear you say, "100 times a year? Are you avin' a laugh? It's all right for you layabout students with your peace marches and your LSD, but some of us have got to work for a livin'." Well, OK, suppose you have sex 20 times a year and use special fundie condoms that break in 3% of uses. Your chance of not experiencing any breaks would be 1 - 0.97^20 = 0.456..., which is to say that you've only got a bit better than a 45% chance of not seeing a broken "condom". Like I said, effectively useless.

Let's return to reality, and try to work out the actual per-use failure rate of real condoms. Suppose, again, that the couples in the studies had sex on average 100 times a year (adjust up or down as you prefer). Then the probability of a given condom not breaking is the 100th root of 0.97, which is 0.999695. So the chance of it breaking is actually 0.03%. If the couples had sex on average 200 times a year, we'd get 1 - (0.97^(1/200)) = 0.015%.

This is important to know about, because the less-scrupulous opponents of contraception will frequently quote per-year failure rates as if they were per-use rates (when they don't just lie outright, that is). And they're right: if condoms did fail on 3% of occasions, there wouldn't be much point in bothering with them. But they're actually much, much better than that. So if anyone ever says "condoms are useless, they fail 3% of the time", now you know what to say to them.

[Beware also the difference between breakage rate (interesting for STD protection) and conception rate (interesting for, well, contraception). Also, according to the site linked above, about half of breakages occur when you're putting the condom on, and are therefore harmless. Assuming you don't do something stupid like say "oh bugger, that was the last one, we'll just have to carry on without one." Mathematics is powerless against such stupidity.]

[identity profile] azrelle.livejournal.com 2007-10-25 08:21 pm (UTC)(link)
Mirena has hormones in it too, so in some cases stops ovulation occuring, definately stops the lining of the womb growing and also act as a physical block in the tubes. As it acts locally it's a lower does of hormones and also leads to reduced period bleeds and in some cases none at all. All the normal side effects and risks of hormones are reduced. There is still a risk of ectopic pregnancy if you are unlucky enough to be in the 0.5% of people in whom there is a failure, but that's still lower than the overal risk for ectopic pregnancy in the general population. I believe there was a paper recently that argued that in women who had already had an ectopic pregnancy and lost one fallopian tube that the Mirena would be the best option for them for contraception as it reduced the risk of ectopics below the normal for the general population and for any means of contraception.

When compared to Depoprovera the Mirena coil beats it on effectiveness and side effect profile in independent studies. The Mirena coil can however be painful to insert in women who have never had a child and that is what puts many women off having it done. Once you've had a kid your cervix is a bit wider and more easily accepts the Mirena going through.

[identity profile] half-of-monty.livejournal.com 2007-10-25 08:27 pm (UTC)(link)
Yes, I think I was thinking of the purely physical coil with ectopic pregnancies (which I see I have been hideously mis-spelling). Thanks, very interesting - in fact now I come to think of it I think a doctor friend has also told me I should try that. Does the lower local dose of hormones effect also mean it's not associated to osteoperosis (which they don't seem to make their mind up on with depo)?

[identity profile] azrelle.livejournal.com 2007-10-25 08:32 pm (UTC)(link)
It's not been on the market long enough to formally study, but in theory as the dose of hormones is much lower it shouldn't have as much of an effect on bone density as COCP or Depo. They can't prove that in actuality yet. A few studies have started to come out on Depo but have had very different conclusions - some say it's better, some say it's worse.